A new adsorption agent for coagulation factors.

نویسنده

  • J P SOULIER
چکیده

The adsorption of coagulation factors was studied in the presence of the following decalcifying agents: Ion exchange resins, ammonium citrate, ammonium oxalate, a mixture of potassium and ammonium oxalate, and sodium E.D.T.A. Whichever decalcifying technique was used, the results were similar and only the results using human citrated plasma (1 part of citrate 0.38% to 9 parts of blood) are reported here. Citrated plasma was exposed to different concentrations of bentonite and the concentration of the various coagulation factors was measured thereafter. The results of these various assays are reported in Table II. When a concentration of bentonite higher than 0.5% was used, it will be seen that the clotting time on recalcification and the Quick prothrombin time were all infinitely long. This suggests that fibrinogen had been adsorbed, a conclusion which was confirmed by the following

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 12  شماره 

صفحات  -

تاریخ انتشار 1959